Symbol
Name
ID

Kcnq1
potassium voltage-gated channel, subfamily Q, member 1
MGI:108083

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Left atrial enlargement

Left ventricular hypertrophy

Right ventricular dilatation

Stroke

Reduced left ventricular ejection fraction

Elevated left ventricular end-diastolic diameter

Aortic valve stenosis

Tricuspid regurgitation

Hypertension

Prolonged P wave

Prolonged PR interval

Prolonged QRS complex

Prolonged QT interval

Prolonged QTc interval

Shortened QT interval

ST segment elevation

Sinus bradycardia

Bradycardia

Cardiac arrest

Sudden cardiac death

Palpitations

Atrial fibrillation

Paroxysmal atrial fibrillation

Permanent atrial fibrillation

Atrial flutter

Premature atrial contractions

Supraventricular tachycardia

Tachycardia

Premature ventricular contraction

Torsade de pointes

Ventricular fibrillation

Myocardial infarction

Syncope

Disease(s) Associated with KCNQ1

familial atrial fibrillation

Jervell-Lange Nielsen syndrome

long QT syndrome 1

short QT syndrome

Mouse Phenotypes		cardiovascular system phenotype	increased heart weight	cardiac hypertrophy	prolonged PR interval	abnormal heart electrocardiography waveform feature	abnormal P wave	increased QRS amplitude	prolonged QRS complex duration	prolonged QT interval	abnormal T wave
Availability	Mouse Genotype	cardiovascular system phenotype	increased heart weight	cardiac hypertrophy	prolonged PR interval	abnormal heart electrocardiography waveform feature	abnormal P wave	increased QRS amplitude	prolonged QRS complex duration	prolonged QT interval	abnormal T wave
	Kcnq1^tm1Apf/Kcnq1^tm1Apf	*
	Kcnq1^tm1Kpfe/Kcnq1^tm1Kpfe
	Kcnq1^tm2Kpfe/Kcnq1^tm2Kpfe
	Kcnq1^tm3Kpfe/Kcnq1^tm3Kpfe
	Kcnq1^tm3Kpfe/Kcnq1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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